Invention Grant
- Patent Title: Method for increasing efficiency of homologous recombination-based gene editing in plant
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Application No.: US16963965Application Date: 2019-01-11
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Publication No.: US11542530B2Publication Date: 2023-01-03
- Inventor: Jae Yean Kim , Tien Van Vu , Velu Sivankalyani , Mil Thi Tran , Jihae Kim , Yeon Woo Sung , Se Jeong Jeong , Hyun Jeong Kim
- Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
- Applicant Address: KR Gyeongsangnam-do
- Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
- Current Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
- Current Assignee Address: KR Gyeongsangnam-do
- Agency: The PL Law Group, PLLC
- Priority: KR10-2018-0007579 20180122
- International Application: PCT/KR2019/000501 WO 20190111
- International Announcement: WO2019/143077 WO 20190725
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N15/90 ; C12N9/22 ; C12N15/113
Abstract:
A method for increasing the efficiency of homologous recombination-based gene editing in a plant according to an embodiment of the present invention includes optimizing temperature and photoperiod conditions during tissue culture of plant cells, expressing factors required for homology-directed DNA repair (HDR) and factors for increasing the HDR efficiency by using a multiple replicon, or regulating the HDR pathway or non-homologous end joining (NHEJ) pathway.
Public/Granted literature
- US20210040505A1 METHOD FOR INCREASING EFFICIENCY OF HOMOLOGOUS RECOMBINATION-BASED GENE EDITING IN PLANT Public/Granted day:2021-02-11
Information query
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