Invention Grant
- Patent Title: BAG3 as a target for therapy of heart failure
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Application No.: US15929784Application Date: 2020-05-21
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Publication No.: US11542555B2Publication Date: 2023-01-03
- Inventor: Arthur M. Feldman , Douglas G. Tilley , Weizhong Zhu , Kamel Khalili , Walter J. Koch
- Applicant: TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Applicant Address: US PA Philadelphia
- Assignee: TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Current Assignee: TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Current Assignee Address: US PA Philadelphia
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Agent Robert M. Bedgood
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; G01N33/68 ; A61K48/00

Abstract:
Compositions are directed to BCL2-associated athanogene 3 (BAG3) molecules and agents which modulate expression of BAG3 molecules. Pharmaceutical composition for administration to patients, for example, patients with heart failure, comprise one or more BAG3 molecules or agents which modulate expression of BAG3. Methods of treatment and identifying candidate therapeutic agents are also provided.
Public/Granted literature
- US20210017600A1 BAG3 AS A TARGET FOR THERAPY OF HEART FAILURE Public/Granted day:2021-01-21
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