The present invention discloses a networked control system (NCS) time-delay compensation method based on predictive control. The method comprises the following steps: (1) acquiring random time-delay data in an NCS, and preprocessing the data; (2) predicting the current time-delay by using a fuzzy neural network (FNN) optimized by a particle swarm optimization (PSO) algorithm; (3) compensating the predicted time-delay by using an implicit proportional-integral-based generalized predictive control (PIGPC) algorithm; (4) determining whether a preset work end time is up according to a clock in the NCS; if yes, ending the process; if no, returning to step (2). The method disclosed by the present invention can accurately predict and effectively compensate the NCS time-delay and has excellent development prospect.