A method for operating an environment sensor system of a vehicle, in particular of an autonomous motor vehicle, and an environment sensor system. The method includes the steps: producing first image data from a first image of a vehicle environment with the aid of a first sensor, performing a setpoint-actual comparison of the first image data with the second image data, and recognizing an operability of the environment sensor system based on the setpoint-actual comparison, the second image data including standard image data and/or image information from a second image of the vehicle environment, and the operability being recognized with the aid of a first artificial intelligence.