A method to perform automatic corneal topography or tomography difference mapping includes receiving one or more corneal topography or tomography data files and/or a corneal image for an examined patient from a corneal topography or tomography system; receiving personal identification parameters from captured user personal data communicated from the corneal topography or tomography system; and comparing received patient identification parameters to existing patient identification parameters in a database to identify if there are existing topography or tomography data files for a same patient in the database. The method may further include retrieving a prior topography or tomography data file for the patient from the database; and performing difference mapping by comparing the received topography or tomography data files to the prior topography or tomography data file retrieved from the database to generate a topography or tomography difference map.