Invention Grant
- Patent Title: Vaccine nanotechnology
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Application No.: US16544464Application Date: 2019-08-19
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Publication No.: US11547667B2Publication Date: 2023-01-10
- Inventor: Ulrich H. von Andrian , Omid C. Farokhzad , Robert S. Langer , Tobias Junt , Elliott Ashley Moseman , Liangfang Zhang , Pamela Basto , Matteo Iannacone , Frank Alexis
- Applicant: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , President and Fellows of Harvard College , The Children's Medical Center Corporation
- Applicant Address: US MA Cambridge; US MA Boston; US MA Cambridge; US MA Boston
- Assignee: Massachusetts Institute of Technology,The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,The Children's Medical Center Corporation
- Current Assignee: Massachusetts Institute of Technology,The Brigham and Women's Hospital, Inc.,President and Fellows of Harvard College,The Children's Medical Center Corporation
- Current Assignee Address: US MA Cambridge; US MA Boston; US MA Cambridge; US MA Boston
- Agency: Pabst Patent Group LLP
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K39/00 ; A61K47/69 ; A61K39/39 ; A61K39/12
Abstract:
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at least one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.
Public/Granted literature
- US20200054559A1 VACCINE NANOTECHNOLOGY Public/Granted day:2020-02-20
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