Invention Grant
- Patent Title: Use of formin agonists in overcoming brain tumor radio- and chemo-resistance by targeting tumor microtubes
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Application No.: US16814425Application Date: 2020-03-10
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Publication No.: US11547682B2Publication Date: 2023-01-10
- Inventor: Kathryn Eisenmann , Krista M. Pettee , Kathryn Becker
- Applicant: The University of Toledo
- Applicant Address: US OH Toledo
- Assignee: The University of Toledo
- Current Assignee: The University of Toledo
- Current Assignee Address: US OH Toledo
- Agency: MacMillan, Sobanski & Todd, LLC
- Main IPC: A61K31/175
- IPC: A61K31/175 ; A61P35/00 ; A61K45/06
Abstract:
Compositions and methods for inhibiting brain tumor proliferation, or for inhibiting or halting TM formation, invasion, and/or proliferation, or for rendering brain tumor cells sensitive to chemotherapy or radiation, or for treating a brain tumor, or for inducing cell death, involving mDia agonists such as IMM01 and IMM02, are described.
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