Invention Grant
- Patent Title: Use of chlorogenic acid in preparation of drug for treating chordoma
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Application No.: US16958881Application Date: 2018-12-27
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Publication No.: US11547715B2Publication Date: 2023-01-10
- Inventor: Jie Zhang , Yazhuo Zhang , Mengtian Zhang
- Applicant: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD
- Applicant Address: CN Sichuan
- Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD
- Current Assignee: SICHUAN JIUZHANG BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD
- Current Assignee Address: CN Sichuan
- Agency: Novick, Kim & Lee, PLLC
- Agent Allen Xue
- Priority: CN201711465147.8 20171228
- International Application: PCT/CN2018/124310 WO 20181227
- International Announcement: WO2019/129135 WO 20190704
- Main IPC: A61K31/7034
- IPC: A61K31/7034 ; A61P35/00 ; A61K9/00 ; A61K9/19
Abstract:
A drug that contains chlorogenic acid is effective in treating chordoma. When administered to a patient in need thereof, chlorogenic acid can significantly inhibit the proliferation of chordoma cells, reduce the expression level of multi-drug resistance gene MDR1 of chordoma cells, reverse the multi-drug resistance of chordoma cells, and effectively treat chordoma disease.
Public/Granted literature
- US20200338104A1 USE OF CHLOROGENIC ACID IN PREPARATION OF DRUG FOR TREATING CHORDOMA Public/Granted day:2020-10-29
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