Invention Grant
- Patent Title: Systems and methods for preparing corneal tissue for implant
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Application No.: US16800059Application Date: 2020-02-25
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Publication No.: US11547778B2Publication Date: 2023-01-10
- Inventor: Edward J. Holland , Kevin Potts , Timothy G. Baldwin
- Applicant: CorneaGen Inc.
- Applicant Address: US WA Seattle
- Assignee: CorneaGen Inc.
- Current Assignee: CorneaGen Inc.
- Current Assignee Address: US WA Seattle
- Agency: Polsinelli PC
- Main IPC: A61L27/36
- IPC: A61L27/36 ; A61F2/14 ; A61F9/007 ; A61F9/013

Abstract:
A technique can consistently achieve thicknesses of ≤50 μm for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ≤50 μm are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ≤100 μm, or more particularly ≤50 μm, to produce a corneal graft.
Public/Granted literature
- US20200268941A1 SYSTEMS AND METHODS FOR PREPARING CORNEAL TISSUE FOR IMPLANT Public/Granted day:2020-08-27
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