Systems, vehicles and methods for determining wrong direction driving are disclosed. In one embodiment, a system for determining a vehicle traveling in a wrong direction includes one or more sensors that produce sensor data, one or more processors, and one or more non-transitory computer-readable medium storing computer readable-instructions. When the computer-readable instructions are executed by the one or more processors, the computer-readable instructions cause the one or more processors to determine one or more lanes within a roadway using the sensor data, determine a direction of travel of the one or more lanes using the sensor data, and identify a non-compliant vehicle traveling in a direction in the one or more lanes that is different from the determined direction of travel in the one or more lanes.