Invention Grant
- Patent Title: Biodegradable compound, lipid particle, composition comprising lipid particle, and kit
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Application No.: US16812625Application Date: 2020-03-09
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Publication No.: US11548857B2Publication Date: 2023-01-10
- Inventor: Mitsuko Ishihara , Eiichi Akahoshi , Katsuyuki Naito , Emi Nozaki , Saeko Saruwatari
- Applicant: KABUSHIKI KAISHA TOSHIBA
- Applicant Address: JP Minato-ku
- Assignee: KABUSHIKI KAISHA TOSHIBA
- Current Assignee: KABUSHIKI KAISHA TOSHIBA
- Current Assignee Address: JP Minato-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JPJP2018-154955 20180821
- Main IPC: C07D243/08
- IPC: C07D243/08 ; C07C229/30 ; C07D233/02 ; C07D241/04 ; C07D211/14 ; A61K9/127 ; A61K31/7088
Abstract:
The present embodiment provides a compound represented by the formula (1): Q-CHR2 (1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.
Public/Granted literature
- US20200270217A1 BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT Public/Granted day:2020-08-27
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