Invention Grant
- Patent Title: Emopamil binding protein binding agent and use thereof
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Application No.: US16760512Application Date: 2018-10-30
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Publication No.: US11548878B2Publication Date: 2023-01-10
- Inventor: Takeaki Yano , Kaori Miyamoto , Koichi Saito
- Applicant: FUJIFILM Toyama Chemical Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: FUJIFILM Toyama Chemical Co., Ltd.
- Current Assignee: FUJIFILM Toyama Chemical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JPJP2017-209391 20171030
- International Application: PCT/JP2018/040283 WO 20181030
- International Announcement: WO2019/088083 WO 20190509
- Main IPC: C07D409/12
- IPC: C07D409/12 ; A61K31/397

Abstract:
Required are: a compound having high affinity for an emopamil binding protein; and a method for activating or inhibiting the emopamil binding protein, using such a compound. According to the present invention, provided is an emopamil binding protein binding agent comprising an alkyl ether derivative represented by the following formula [1] or a salt thereof: wherein R1 and R2, which are the same or different, each represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted aryl group, etc.; R3 represents an optionally protected hydroxyl group, etc.; and m and n, which are the same or different, each represent an integer of 1 to 6.
Public/Granted literature
- US11479547B2 Emopamil binding protein binding agent and use thereof Public/Granted day:2022-10-25
Information query