Invention Grant
- Patent Title: KRas G12C inhibitors
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Application No.: US16917128Application Date: 2020-06-30
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Publication No.: US11548888B2Publication Date: 2023-01-10
- Inventor: Matthew Arnold Marx , James Gail Christensen , Christopher Ronald Smith , John P Fischer , Aaron Craig Burns
- Applicant: Mirati Therapeutics, Inc. , Array BioPharma, Inc.
- Applicant Address: US CA San Diego; US CO Boulder
- Assignee: Mirati Therapeutics, Inc.,Array BioPharma, Inc.
- Current Assignee: Mirati Therapeutics, Inc.,Array BioPharma, Inc.
- Current Assignee Address: US CA San Diego; US CO Boulder
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D519/00 ; A61P35/00
Abstract:
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
Public/Granted literature
- US20200331911A1 KRAS G12C INHIBITORS Public/Granted day:2020-10-22
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