- Patent Title: Engineered platelets for targeted delivery of a therapeutic agent
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Application No.: US17508178Application Date: 2021-10-22
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Publication No.: US11548928B2Publication Date: 2023-01-10
- Inventor: James Patterson
- Applicant: JPV01 LTD.
- Applicant Address: GB London
- Assignee: JPV01 LTD.
- Current Assignee: JPV01 LTD.
- Current Assignee Address: GB London
- Agency: RinLaures LLC
- Agent Li-Hsien Rin-Laures; Kristen A. Dola
- Priority: GB1918586 20191217
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K16/28 ; C07K14/735
Abstract:
The present invention provides engineered platelets with chimeric platelet receptors (CPR) with a desired target specificity. Additionally, the engineered platelets may comprise cargo which may be released upon activation of the platelet. Additionally, the platelets may be generated in vitro from megakaryocytes engineered to generate non-thrombogenic platelets.
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