Invention Grant
- Patent Title: Compositions and methods for treatment of thyroid eye disease
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Application No.: US17822978Application Date: 2022-08-29
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Publication No.: US11548951B1Publication Date: 2023-01-10
- Inventor: Vahe Bedian , Peter Harwin , Tomas Kiselak , Angela She , Jonathan Violin , Yang Zhao
- Applicant: Viridian Therapeutics, Inc.
- Applicant Address: US MA Waltham
- Assignee: Viridian Therapeutics, Inc.
- Current Assignee: Viridian Therapeutics, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Troutman Pepper Hamilton Sanders LLP
- Main IPC: A61P27/02
- IPC: A61P27/02 ; C07K16/28 ; A61K9/00 ; A61K39/00

Abstract:
Antibodies and compositions against Insulin-Like Growth Factor-1 Receptor (IGF-1R) and uses thereof are provided herein and antibodies and pharmaceutical compositions that can be used in methods of treating or reducing the severity of thyroid eye disease (TED) in subjects in need thereof, including reducing proptosis and Clinical Activity Score (CAS) in said subjects, by inhibiting the activity of IGF-1R with such antibodies and compositions.
Public/Granted literature
- US20230002495A1 COMPOSITIONS AND METHODS FOR TREATMENT OF THYROID EYE DISEASE Public/Granted day:2023-01-05
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