Invention Grant
- Patent Title: Genetic perturbation of the RNA degradosome protein complex
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Application No.: US16314953Application Date: 2017-06-27
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Publication No.: US11549096B2Publication Date: 2023-01-10
- Inventor: Shawn Manchester
- Applicant: Zymergen Inc.
- Applicant Address: US CA Emeryville
- Assignee: Zymergen Inc.
- Current Assignee: Zymergen Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Cooley LLP
- International Application: PCT/US2017/039452 WO 20170627
- International Announcement: WO2018/009372 WO 20180111
- Main IPC: C12N15/77
- IPC: C12N15/77 ; C12P7/04 ; C12P7/06 ; C12N1/20 ; C07K14/34 ; C12P13/04 ; C12P1/04 ; C12P7/40 ; C12P7/46 ; C12P7/56 ; C12P7/58 ; C12P13/06 ; C12P13/08 ; C12P13/12 ; C12P13/20 ; C12P13/22 ; C12R1/15
Abstract:
The present disclosure provides novel bacterial strains with altered expression or start codon modification of one or more RNA degradation/processing genes. The RNA degradation genes of the present disclosure are controlled by heterologous promoters. The present disclosure further describes methods for generating microbial strains comprising heterologous promoter sequences operably linked to RNA degradation/processing genes.
Public/Granted literature
- US20190194769A1 GENETIC PERTURBATION OF THE RNA DEGRADOSOME PROTEIN COMPLEX Public/Granted day:2019-06-27
Information query
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