A cable holder prevents fraying or tangling of cables configured to physically and electrically connect to one or more devices, such as patient monitoring devices. The cable holder can be configured to: (i) detachably secure the one or more cables, and (ii) be detachably secured to a support structure. The cable holder may include a first surface in which an aperture configured to receive a cable is defined, and a second surface on which a connector configured to removably interconnect with a connector of another cable holder is defined.