Methods, apparatus, systems and articles of manufacture to perform graphics processing on combinations of graphic processing units and digital signal processors are disclosed. A disclosed example method includes processing first data representing input vertices to create second data, the first data using a first format organized by vertex, the second data using a second format organized by components of the vertices. A digital signal processor (DSP) is to perform vertex shading on the second data to create third data, the third data formatted using the second format, the vertex shading performed by executing a first instruction at the DSP, the first instruction generated based on a second instruction capable of being executed at a graphics processing unit (GPU). The third data is processed to create fourth data, the fourth data formatted using the first format.