Provided are a data transmission method and a network device, the method including: configuring a multiple access mode of uplink transmission for a terminal device; sending the multiple access mode of uplink transmission to the terminal device. The multiple access mode of uplink transmission is used for the terminal device to determine a multiplexing mode of a first uplink signal and a second uplink signal on a target time domain resource, wherein the first uplink signal and the second uplink signal are signals which the terminal device is scheduled to transmit on the target time domain resource simultaneously.