Invention Grant
- Patent Title: Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
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Application No.: US17122786Application Date: 2020-12-15
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Publication No.: US11559582B2Publication Date: 2023-01-24
- Inventor: Daulet Satpayev , Robert Kendall Morrison , Karen Jane Meyrick Morrison , Jean Gudas , Aya Jakobovits , Michael Torgov , Zili An
- Applicant: AGENSYS, INC. , SEAGEN INC.
- Applicant Address: US CA Santa Monica; US WA Bothell
- Assignee: AGENSYS, INC.,SEAGEN INC.
- Current Assignee: AGENSYS, INC.,SEAGEN INC.
- Current Assignee Address: US CA Santa Monica; US WA Bothell
- Agency: Jones Day
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K47/68 ; C07K16/30 ; A61K39/00
Abstract:
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
Public/Granted literature
- US20210283268A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS Public/Granted day:2021-09-16
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