Invention Grant
- Patent Title: Granzyme B directed imaging and therapy
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Application No.: US16314134Application Date: 2017-06-30
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Publication No.: US11559590B2Publication Date: 2023-01-24
- Inventor: Umar Mahmood , Benjamin Larimer , Eric Wehrenberg-Klee
- Applicant: The General Hospital Corporation
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2017/040212 WO 20170630
- International Announcement: WO2018/005926 WO 20180104
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61K51/04 ; A61P35/00 ; A61B5/00 ; C12Q1/37 ; C12Q1/34 ; C12Q1/02 ; A61K51/10 ; A61B6/03

Abstract:
Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.
Public/Granted literature
- US20190224348A1 Granzyme B Directed Imaging and Therapy Public/Granted day:2019-07-25
Information query