Invention Grant
- Patent Title: Sulfonylurea compounds as inhibitors of interleukin-1 activity
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Application No.: US17150380Application Date: 2021-01-15
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Publication No.: US11560391B2Publication Date: 2023-01-24
- Inventor: Jeffrey A. Stafford , James M. Veal , Lynnie Lin Trzoss , Christopher McBride , Richard M. Pastor , Steven Thomas Staben , Craig Stivala , Matthew Volgraf
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Katherine J. Mackenzie
- Main IPC: C07D498/04
- IPC: C07D498/04
Abstract:
The present disclosure relates to novel sulfonylurea compounds and related compounds useful in treating a disorder responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.
Public/Granted literature
- US20210261568A1 SULFONYLUREA COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY Public/Granted day:2021-08-26
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