Invention Grant
- Patent Title: Isolated monoclonal antibodies and/or antigen-binding fragments thereof against indoxyl sulfate and uses thereof
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Application No.: US16902006Application Date: 2020-06-15
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Publication No.: US11560423B2Publication Date: 2023-01-24
- Inventor: Yung-Chun Chuang , Yu-Wei Cheng , Chih-Hui Kao
- Applicant: LEADGENE BIOMEDICAL, INC.
- Applicant Address: TW Tainan
- Assignee: LEADGENE BIOMEDICAL, INC.
- Current Assignee: LEADGENE BIOMEDICAL, INC.
- Current Assignee Address: TW Tainan
- Agency: Fay Sharpe LLP
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61P39/00 ; G01N33/53 ; A61K39/00
Abstract:
The present invention relates to isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods applied in theragnosis of IS-related diseases.
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