Invention Grant
- Patent Title: Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders
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Application No.: US16618881Application Date: 2018-06-08
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Publication No.: US11560426B2Publication Date: 2023-01-24
- Inventor: Armin Ehninger
- Applicant: AvenCell Europe GmbH
- Applicant Address: DE Dresden
- Assignee: AvenCell Europe GmbH
- Current Assignee: AvenCell Europe GmbH
- Current Assignee Address: DE Dresden
- Agency: Choate, Hall & Stewart LLP
- Agent Charles E. Lyon
- Priority: EP17175124 20170609
- International Application: PCT/EP2018/065193 WO 20180608
- International Announcement: WO2018/224660 WO 20181213
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/55 ; C07K14/725 ; C07K14/705 ; A61K38/10 ; A61K38/31 ; A61K38/22 ; A61K38/26 ; A61K47/62 ; A61K38/18 ; A61K38/00
Abstract:
The present invention relates to a targeting module comprising a chemically synthesized peptide binding moiety specific for a human cell surface protein or protein complex, a kit comprising the targeting module and a vector or a cell comprising a nucleic acid encoding a universal chimeric antigen receptor and the use for the treatment of cancer, infections and autoimmune disorders.
Information query
