Invention Grant
- Patent Title: Methods of treatment by targeting VCAM1 and MAEA
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Application No.: US16773907Application Date: 2020-01-27
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Publication No.: US11560433B2Publication Date: 2023-01-24
- Inventor: Paul S. Frenette , Sandra Pinho , Qiaozhi Wei , Sung Kyun Lee
- Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Applicant Address: US NY Bronx
- Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
- Current Assignee Address: US NY Bronx
- Agency: Perkins Coie LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/28 ; A61P35/02
Abstract:
Antibodies and antibody fragments that inhibit the activity of vascular cell adhesion molecule 1 (VCAM1) and/or macrophage erythroblast attacher (MAEA) are provided, along with formulations and kits comprising these antibodies and antibody fragments and the use of the disclosed compositions, formulations, and kits to treat cancers, sickle cell disease, and Polycythemia Vera.
Public/Granted literature
- US20200270349A1 METHODS OF TREATMENT BY TARGETING VCAM1 AND MAEA Public/Granted day:2020-08-27
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