A tolerance compensation device includes a base device having a tubular fastening portion that includes an internal, right-hand thread for receiving a screw-like fastening element. A tubular connecting portion, for connecting to a compensation structure, has an outer jacket wall that includes an external thread for connecting to a compensation structure, and a compensation structure having a flange-like setting element. An inner jacket wall of the setting element includes a threading configured to correspond to the external thread, and a socket-like anti-rotation element is disposed in a through-opening of the setting element, and an outer jacket wall of the anti-rotation element is connected to an inner jacket wall of the tubular connecting portion in a non-rotatable manner. The compensation structure is configured for presetting a distance in axial direction between the base device and a contact wall of the compensation structure extending orthogonally to the axial direction.