The present invention is a modification of a typical single mixed refrigerant (SMR) cycle for LNG re-liquefaction in particular, that allows the use of a cost-efficient oil-injected screw compressor in the mixed refrigerant system. In comparison with the typical arrangement, the present innovation allows for reduced complexity, fewer pieces of equipment, and reduced capital cost. There is shown a method of cooling a boil-off gas (BOG) stream from a liquefied gas tank using a single mixed refrigerant (SMR) comprising at least the step of heat exchanging the BOG stream with the SMR in a liquefaction heat exchanger system to provide a cooled BOG stream, wherein the SMR is provided in an SMR recirculating system comprising at least the steps of: (a) compressing the SMR using at least one oil-injected screw compressor to provide a post-compression SMR stream; (b) separating the post-compression SMR stream to provide an oil-based stream and a first SMR vapour stream; (c) passing the first SMR vapour stream into the liquefaction heat exchanger system to cool the first SMR vapour stream and provide a cooled first SMR vapour stream; (d) withdrawing the cooled first SMR vapour stream from the liquefaction heat exchanger system; (e) separating the cooled first SMR vapour stream to provide a liquid-phase SMR stream and an oil-free SMR vapour stream; (f) passing the oil-free SMR vapour stream through the liquefaction heat exchanger system to provide a condensed SMR stream; and (g) expanding the condensed SMR stream to provide an expanded lowest-temperature SMR stream to pass through the liquefaction heat exchanger system for heat exchange against the BOG stream.