Invention Grant
- Patent Title: Therapeutic use of bone morphogenetic proteins
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Application No.: US16415006Application Date: 2019-05-17
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Publication No.: US11572396B2Publication Date: 2023-02-07
- Inventor: Nicholas W. Morrell , Wei Li , Paul D Upton
- Applicant: CAMBRIDGE ENTERPRISE LIMITED
- Applicant Address: GB Cambridge
- Assignee: CAMBRIDGE ENTERPRISE LIMITED
- Current Assignee: CAMBRIDGE ENTERPRISE LIMITED
- Current Assignee Address: GB Cambridge
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: GB1412290 20140710
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K38/00 ; C07K14/51 ; A61K48/00
Abstract:
The invention relates to a polypeptide selected from bone morphogenetic protein 10 (BMP10), or a bone morphogenetic protein 9 (BMP9) variant lacking osteogenic activity, for use in the treatment of a vascular disease or a respiratory disease. The invention also relates to novel BMP9 variants and to pharmaceutical compositions comprising said polypeptides.
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