Invention Grant
- Patent Title: Genetically encoded calcium indicators and methods of use
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Application No.: US16198166Application Date: 2018-11-21
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Publication No.: US11572401B2Publication Date: 2023-02-07
- Inventor: Douglas Kim , Karel Svoboda , Loren Looger , Eric Schreiter
- Applicant: Howard Hughes Medical Institute
- Applicant Address: US MD Chevy Chase
- Assignee: Howard Hughes Medical Institute
- Current Assignee: Howard Hughes Medical Institute
- Current Assignee Address: US MD Chevy Chase
- Agency: Fish & Richardson P.C.
- Main IPC: C07K14/72
- IPC: C07K14/72 ; A61K38/00 ; C12N15/85 ; G01N33/50
Abstract:
Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.
Public/Granted literature
- US20190153067A1 GENETICALLY ENCODED CALCIUM INDICATORS AND METHODS OF USE Public/Granted day:2019-05-23
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