Invention Grant
- Patent Title: Multivalent FV antibodies
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Application No.: US15950733Application Date: 2018-04-11
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Publication No.: US11572415B2Publication Date: 2023-02-07
- Inventor: Kristina Ellwanger , Ivica Fucek , Thorsten Ross , Thomas Mueller , Erich Rajkovic , Uwe Reusch , Martin Treder , Michael Weichel
- Applicant: Affimed GmbH
- Applicant Address: DE Heidelberg
- Assignee: Affimed GmbH
- Current Assignee: Affimed GmbH
- Current Assignee Address: DE Heidelberg
- Agency: Duane Morris LLP
- Agent Thomas J. Kowalski; Deborah L. Lu
- Priority: EP15189665 20151013
- Main IPC: C07K16/46
- IPC: C07K16/46 ; C07K16/28 ; C07K16/08 ; C07K16/30

Abstract:
The application pertains to a trispecific antibody molecule which may comprise a diabody-unit integrated into a polypeptide chain having at least six variable domains linked one after another. In certain instances two single-chain Fv (scFv) fragments are distally connected to the diabody-unit providing two further antigen binding sites (FIGS. 1 and 2).
Public/Granted literature
- US20190040155A1 MULTIVALENT FV ANTIBODIES Public/Granted day:2019-02-07
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