The present disclosure relates to the technical field of pigment dispersing agents, and provides an acrylate comb dispersing agent and a preparation method and use thereof, and a white ink-jet color paste and a preparation method thereof. The dispersing agent provided by the present disclosure is similar to a comb in structure and is synthesized from a hydrophobic monomer (comb handle) and a hydrophilic macromonomer (comb teeth). The acrylate comb dispersing agent provided by the present disclosure is good in dispersity, capable of stably dispersing titanium dioxide, relatively low in molecular weight and capable of meeting the requirements of ink-jet ink. The white ink-jet color paste provided by the present disclosure is strong in stability and low in viscosity, is not easy to settle and flocculate, and meets the requirements of the ink-jet ink.