Invention Grant
- Patent Title: Method for prediction of acute rejection and renal allograft loss using pre-transplant transcriptomic signatures in recipient blood
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Application No.: US17046692Application Date: 2019-04-16
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Publication No.: US11572589B2Publication Date: 2023-02-07
- Inventor: Barbara Murphy , Weijia Zhang
- Applicant: Icahn School of Medicine at Mount Sinai
- Applicant Address: US NY New York
- Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee Address: US NY New York
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2019/027618 WO 20190416
- International Announcement: WO2019/204267 WO 20191024
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883
Abstract:
Disclosed herein are gene signature sets expressed by kidney allograft recipients prior to transplant that determine the risk for acute rejection (AR) post-transplant and methods of using the gene signature sets for identifying renal allograft recipients at risk for acute rejection. Also disclosed herein are kits for use in the invention which comprise primer pairs for the gene signature sets.
Public/Granted literature
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