Invention Grant
- Patent Title: Amplification-integrated genetic material depletion of non-target organisms using differentially abundant k-mers
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Application No.: US16469634Application Date: 2017-11-28
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Publication No.: US11572593B2Publication Date: 2023-02-07
- Inventor: Carsten Dietrich , Yiwei Huang , Mark Matzas , Andreas Emanuel Posch
- Applicant: Siemens Healthcare GmbH
- Applicant Address: DE Erlangen
- Assignee: Siemens Healthcare GmbH
- Current Assignee: Siemens Healthcare GmbH
- Current Assignee Address: DE Erlangen
- Agency: BakerHostetler
- Priority: EP16205822 20161221
- International Application: PCT/EP2017/080666 WO 20171128
- International Announcement: WO2018/114243 WO 20180628
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/70 ; C12Q1/6893 ; C12Q1/689 ; C12Q1/6895
Abstract:
The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers 3 are applied that show a difference in frequency and/or context in the genome 2 of the at least one microorganism and/or virus compared to the genome of the subject 1.
Information query
