A home automation (HA) system may include at least one HA operation device that includes a user-settable thermostat for controlling a heating, ventilation, and air-conditioning (HVAC) system associated with a living area of a user. The HA system may also include a controller. The controller may be configured to collect user thermostat setting data from the user-settable thermostat, and use machine learning to identify a health condition of the user based upon the user thermostat setting data.