Invention Grant
- Patent Title: Total cellular iron as a marker of cancer stem cells and uses thereof
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Application No.: US16082970Application Date: 2017-03-08
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Publication No.: US11573241B2Publication Date: 2023-02-07
- Inventor: Maryam Mehrpour , Raphael Rodriguez , Ahmed Hamai , Trang Mai
- Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM) , Centre National de la Recherche Scientifique (CNRS) , Universite Paris Descartes
- Applicant Address: FR Paris; FR Paris; FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Universite Paris Descartes
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Universite Paris Descartes
- Current Assignee Address: FR Paris; FR Paris; FR Paris
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Erin M. Dunston
- Priority: EP16305266 20160309
- International Application: PCT/EP2017/055450 WO 20170308
- International Announcement: WO2017/153475 WO 20170914
- Main IPC: G01N33/84
- IPC: G01N33/84 ; G01N33/574 ; A61K31/7048
Abstract:
The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.
Public/Granted literature
- US20190101549A1 TOTAL CELLULAR IRON AS A MARKER OF CANCER STEM CELLS AND USES THEREOF Public/Granted day:2019-04-04
Information query
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