Methods, apparatus, systems, computing devices, computing entities, and/or the like for programmatically generating multi-paradigm feature representations are provided. An example method may include generating a code dataset including a plurality of codes associated with a predictive entity; generating a plurality of semantic feature vectors based at least in part on code description metadata; generating a plurality of structural feature vectors based at least in part on code relation metadata; generating a plurality of multi-paradigm feature vectors based at least in part on the plurality of semantic feature vectors and the plurality of structural feature vectors; generating a prediction for the predictive entity by processing the plurality of multi-paradigm feature vectors using a prediction model; and performing one or more prediction-based actions based on the prediction.