A multi-communication path selection and security system for a medical device includes a medical device and a computer. The medical device includes a processor, one or more communication interfaces, and a memory that stores configurable settings, medical device policies and profiles associated with a plurality of communication links. The processor establishes a location variable associated with the medical device and when the location variable exceeds a location proximity threshold, the processor alters one or more settings of the medical device based on the medical device policies. The processor establishes a source location variable associated with the computer or an incoming message from the computer, and when the source location variable exceeds a source proximity threshold, the processor alters the incoming message or the settings of the medical device based on the medical device policies.