Data may be encoded to minimize distortion after decoding, but the quality required for presentation of the decoded data to a machine and the quality required for presentation to a human may be different. To accommodate different quality requirements, video data may be encoded to produce a first set of encoded data and a second set of encoded data, where the first set may be decoded for use by one of a machine consumer or a human consumer, and a combination of the first set and the second set may be decoded for use by the other of a machine consumer or a human consumer. The first and second set may be produced with a neural encoder and a neural decoder, and/or may be produced with the use of prediction and transform neural network modules. A human-targeted structure and a machine-targeted structure may produce the sets of encoded data.