- Patent Title: Injectable solution at pH 7 comprising at least one basal insulin for which the pI is from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals
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Application No.: US16641383Application Date: 2018-08-24
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Publication No.: US11576952B2Publication Date: 2023-02-14
- Inventor: Richard Charvet
- Applicant: ADOCIA
- Applicant Address: FR Lyons
- Assignee: ADOCIA
- Current Assignee: ADOCIA
- Current Assignee Address: FR Lyons
- Agency: Oliff PLC
- Priority: FR1757860 20170824
- International Application: PCT/EP2018/072936 WO 20180824
- International Announcement: WO2019/038445 WO 20190228
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/28 ; A61K9/00 ; A61K38/26 ; A61K47/42

Abstract:
A composition in the form of an injectable aqueous solution, whose pH consists from 6.0 to 8.0, including at least: a basal insulin whose isoelectric point includes from 5.8 to 8.5; a co-polyamino-acid bearing carboxylate charges and hydrophobic radicals Hy, the co-polyamino-acid being constituted of glutamic or aspartic units and said hydrophobic radicals Hy according to the following formula I:
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