A method for manufacturing a multi-functional fastener includes a preparing operation, a forming operation and a threading operation. The preparing operation prepares a metal blank cut from a length of a metal material. The forming operation is executed so that the metal blank forms a shank, a head, and a drilling portion connected to the shank. The threading operation is executed to roll the metal blank with a thread rolling set having two opposite rolling plates. Each rolling plate has slit grooves and convex units arranged in alternation. Each of the convex units has protrusions each situated between two adjacent slit grooves, which allows the threading operation to equip the shank of the metal blank with thread convolutions, slots formed between the thread convolutions for helping quick removal of chips, and main ribs formed between any two adjacent slots for increasing cutting efficiency.