Invention Grant
- Patent Title: Method for producing CD4/CD8 double-positive T cells
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Application No.: US16312789Application Date: 2017-06-21
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Publication No.: US11578310B2Publication Date: 2023-02-14
- Inventor: Shin Kaneko , Yutaka Yasui , Shoichi Iriguchi , Tatsuki Ueda
- Applicant: Kyoto University
- Applicant Address: JP Kyoto
- Assignee: Kyoto University
- Current Assignee: Kyoto University
- Current Assignee Address: JP Kyoto
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: JPJP2016-124924 20160623
- International Application: PCT/JP2017/022840 WO 20170621
- International Announcement: WO2017/221975 WO 20171228
- Main IPC: C12N5/074
- IPC: C12N5/074 ; C07D401/04 ; C07K14/725 ; C12N5/0783 ; C12N5/10 ; C12N15/85
Abstract:
A method for producing CD4/CD8 double-positive T cells, comprising the steps of: (1) culturing pluripotent stem cells in a medium to induce hematopoietic progenitor cells; and (2) culturing the hematopoietic progenitor cells obtained in the step (1) in a medium containing a p38 inhibitor and/or SDF-1 to induce CD4/CD8 double-positive T cells.
Public/Granted literature
- US20190330596A1 METHOD FOR PRODUCING CD4/CD8 DOUBLE-POSITIVE T CELLS Public/Granted day:2019-10-31
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