A method (100) of route selection in a wireless communication system and a control system (40) is provided. The method includes selecting a route between a first node (1) and a second node (2) and comprises: —evaluating (110) a plurality of possible routes (R1, R2, R3, R4), at least one route (R2, R3, R4) including a third node (3, 4) between the first and the second node; and —selecting (160) the route that has the lowest latency among the possible routes. Especially the method (100) includes: —selecting (120) parameter settings for each link of the possible routes, said selecting (120) comprising; —selecting (130) the length of the cyclic prefix, —evaluating (140) combinations of the selected cyclic prefix and different settings of the at least one further parameter of the physical layer; —selecting (150) the parameter settings that has lowest estimated latency and fulfils at least one communication quality criterion.