A coffee grinder-loser apparatus has a removable grinding chamber that is extractable with a fast release. Grinding adjustment is independent of access to the grinding chamber. An interface flange is interposed between an adjusting ring nut and a fixed chamber of the grinding chamber. The flange makes an indirect coupling of the ring nut and of an extractable group of components to the fixed structure. A locking system includes levers with a cam tooth mounted externally on the interface flange. The cam tooth hooks a head of tie-rod assemblies with an elastic spring so as to place them in traction and joined to the fixed structure of the grinding chamber.