- Patent Title: Device for recording the vascular response of the human spinal cord triggered by a suprasensible stimulus through the use of functional near-infrared spectroscopy
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Application No.: US16958433Application Date: 2018-12-27
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Publication No.: US11583201B2Publication Date: 2023-02-21
- Inventor: Felipe Ignacio Valenzuela Beck , Sergio Andres Uribe Arancibia , Antonio Alejandro Eblen Zajjur , Ranganatha Sitaram , Mohit Rana
- Applicant: PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
- Applicant Address: CL Santiago
- Assignee: PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
- Current Assignee: PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
- Current Assignee Address: CL Santiago
- Agency: Raphael Bellum PLLC
- Priority: CL3462-2017 20171228
- International Application: PCT/CL2018/050155 WO 20181227
- International Announcement: WO2019/126898 WO 20190704
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B5/026 ; A61N1/36

Abstract:
The invention consists of a device to evaluate hemodynamic response generated by the spinal cord in response to a suprasensorial stimulus applied to a peripheral nerve (medium or posterior tibial) by the use of functional near-infrared spectroscopy (fNIRS). The device consists of 3 main components, an electrical stimulator, an optical recording unit and a signal processing and control module. The device allows non-invasive, comfortable, harmless, portable, home-based, and low-cost evaluation of changes in local hemodynamic parameters in response to neuronal activation of the spinal cord by electrical stimulation of a peripheral nerve. The invention also includes a corresponding method of using the device and monitoring the spinal function.
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