Invention Grant
- Patent Title: Treating progressive familial intrahepatic cholestasis (PFIC) with IBAT inhibitors
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Application No.: US17548090Application Date: 2021-12-10
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Publication No.: US11583539B2Publication Date: 2023-02-21
- Inventor: Per-Göran Gillberg , Jan Mattsson , Pat Horn , Paresh Soni
- Applicant: ALBIREO AB
- Applicant Address: SE Gothenburg
- Assignee: ALBIREO AB
- Current Assignee: ALBIREO AB
- Current Assignee Address: SE Gothenburg
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/554
- IPC: A61K31/554 ; A61P1/16 ; A61K9/16
Abstract:
Provided herein are methods for treating progressive familial intrahepatic cholestasis (PFIC) with an ileal bile acid transport (IBAT) inhibitor such as odevixibat, or a pharmaceutically acceptable salt thereof. Such methods can include reducing mean pruritus score, mean serum bile acid concentration, increasing height, normalizing weight, improving sleep, and improving liver parameters.
Public/Granted literature
- US20220143043A1 Treating Progressive Familial Intrahepatic Cholestasis (PFIC) Public/Granted day:2022-05-12
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