Foldable strollers with removable seats and related methods are disclosed herein. An example stroller disclosed herein a wheeled frame, a receiver coupled to the frame, and a seat. The seat includes a mount, a lock disposed in the mount; and a handle having an extended positon and a retracted position relative to the seat. The lock is to move from a first position to a second position when the mount is disposed in the receiver to removably couple the seat to the frame, and the lock to move from the second position to the first position to release the seat from the receiver when the handle moves from the retracted position to the extended position.