Invention Grant
- Patent Title: Substituted aminothiazoles as inhibitors of nucleases
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Application No.: US17047004Application Date: 2019-04-15
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Publication No.: US11584742B2Publication Date: 2023-02-21
- Inventor: Kamil Paruch , Benoit Carbain , Stepan Havel , Jiri Damborsky , Jan Brezovsky , Lukas Daniel , Alexandra Sisakova , Fedor Nikulenkov , Lumir Krejci
- Applicant: MASARYKOVA UNIVERZITA
- Applicant Address: CZ Brno
- Assignee: MASARYKOVA UNIVERZITA
- Current Assignee: MASARYKOVA UNIVERZITA
- Current Assignee Address: CZ Brno
- Agency: Notaro, Michalos & Zaccaria P.C.
- Priority: EP18167651 20180417
- International Application: PCT/EP2019/059689 WO 20190415
- International Announcement: WO2019/201865 WO 20191024
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D277/46 ; C07D277/60 ; C07D417/12

Abstract:
Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Public/Granted literature
- US20220002282A1 SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES Public/Granted day:2022-01-06
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