Invention Grant
- Patent Title: C-peptides and proinsulin polypeptides comprising the same
-
Application No.: US16866361Application Date: 2020-05-04
-
Publication No.: US11584785B2Publication Date: 2023-02-21
- Inventor: Amy Doerner , Michael Cammarata , Tyler Nusca , Suzanne A. Sprunger , Melissa Patterson
- Applicant: ABSCI, LLC
- Applicant Address: US WA Vancouver
- Assignee: ABSCI, LLC
- Current Assignee: ABSCI, LLC
- Current Assignee Address: US WA Vancouver
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K14/62 ; C12N9/48 ; C12N9/96
Abstract:
A connecting polypeptide has SEQ ID NO:73. A proinsulin polypeptide includes a mature insulin A-chain, a mature insulin B-chain, and a connecting peptide comprising SEQ ID NO: 73 linking the mature A-chain and the mature B-chain, wherein the connecting peptide is not a native human proinsulin C-peptide. The proinsulin polypeptides according to the invention can be made in high titers and in high purity.
Public/Granted literature
- US20200299343A1 C-PEPTIDES AND PROINSULIN POLYPEPTIDES COMPRISING THE SAME Public/Granted day:2020-09-24
Information query
