Invention Grant
- Patent Title: Bispecific heterodimeric fusion proteins containing IL-15-IL-15Ralpha Fc-fusion proteins and immune checkpoint antibody fragments
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Application No.: US16718072Application Date: 2019-12-17
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Publication No.: US11584794B2Publication Date: 2023-02-21
- Inventor: Matthew Bernett , Rumana Rashid , John Desjarlais , Rajat Varma , Christine Bonzon
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Kelly A. Plummer; Christopher J. Betti
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/54 ; C07K14/715 ; C12N15/63 ; A61P35/00 ; A61K38/00 ; A61K39/00
Abstract:
The present invention is directed to novel bispecific heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc-fusion protein and a PD-1 antibody fragment-Fc fusion protein.
Information query
