Invention Grant
- Patent Title: Compositions and methods for improving immune system function
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Application No.: US16317446Application Date: 2017-07-14
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Publication No.: US11584934B2Publication Date: 2023-02-21
- Inventor: Richard P. Junghans , Mumtaz Yaseen
- Applicant: Tufts Medical Center, Inc.
- Applicant Address: US MA Boston
- Assignee: Tufts Medical Center, Inc.
- Current Assignee: Tufts Medical Center, Inc.
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- Agent Susan M. Michaud
- International Application: PCT/US2017/042147 WO 20170714
- International Announcement: WO2018/013929 WO 20180118
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61P31/00 ; A61P35/00 ; A61K31/4439 ; A61K31/444 ; A61K31/496 ; A61K31/5377 ; A61K31/706 ; A61K31/713 ; A61K35/17 ; C12N9/10 ; A61P37/04 ; A61K31/7088 ; A61K31/7105 ; C07K14/47 ; A61K45/06
Abstract:
Provided herein are compositions and methods for improving immune system function. In particular, provided herein are compositions, methods, and uses of YY1 and EZH2 inhibitors for preventing and reversing T-cell exhaustion (e.g., for use in immunotherapy).
Public/Granted literature
- US11624068B2 Compositions and methods for improving immune system function Public/Granted day:2023-04-11
Information query
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